Florence is a top destination in USA, a great place to spend some time on any visit to USA. Discover our selection of hotels in Florence, sorted below by style and amenities, along with our hotel videos to help you make the right choice.

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Travelodge Florence SC -  - photo
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Travelodge Florence SC2 																Stars

3783A W. Palmetto St. - 29502 Florence - See on mapThe budget-friendly Travelodge in Florence is located approximately six miles from the city���s center, and is 12 miles from Florence Regional Airport. Local attractions include Francis Macon University, approximat

$36Check rates*Min. price over next 30 days

Knights Inn Florence -  - photo
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Knights Inn Florence2 																Stars

2038 W. Lucas St - 29501 Florence - See on map24 hour business center, microwave and refrigerator in all rooms, free continental breakfast.

$51Check rates*Min. price over next 30 days

Wingate by Wyndham - Florence -  - photo
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Wingate by Wyndham - Florence3 																Stars

2123 W. Lucas Street - 29501 Florence - See on mapOur convenient airport location (just 10 minutes away) and proximity to shopping, dining and entertainment makes us the hotel of choice among serious business travelers. At Wingate by Wyndham Florence we are prepa

$60Check rates*Min. price over next 30 days

Howard Johnson Florence -  - photo
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Howard Johnson Florence2 																Stars

3821 BANCROFT ROAD - 29501 Florence - See on mapThis Howard Johnson Hotel is situated approximately four miles from Huggins Memorial Airport and nine miles from Florence Regional Airport.<br><br>Hotel amenities include free local telephone calls, free parking, 2

$46Check rates*Min. price over next 30 days

FlorenceCivic Center SC -  - photo
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FlorenceCivic Center SC2 																Stars

3000 West Radio Drive - 29501 Florence - See on mapThe Hampton Inn & Suites Florence-Civic Center hotel is located in South Carolina at the junction of I-95 and I-20, adjacent to the Florence Civic Center and Swamp Fox Cinemas. The Magnolia Mall and the Commons at

$109Check rates*Min. price over next 30 days

Super 8 Florence -  - photo
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Super 8 Florence2 																Stars

1832 1/2 Lucas Street - 29501 Florence - See on mapSuper 8 Florence is located approximately eight miles from Florence Airport and 10 miles from Darlington Raceway. This location is also two miles from a shopping mall, four miles from Florence Civic Center, and fiv

$44Check rates*Min. price over next 30 days

Holiday Inn Express Hotel & Suites FLORENCE I-95 @ HWY 327 -  - photo
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Holiday Inn Express Hotel & Suites FLORENCE I-95 @ HWY 3273 																Stars

2101 FLORENCE HARLLEE BLVD - 29506 Florence - See on mapThis Holiday Inn Express And Suites is located approximately 11 miles from the Florence Regional Airport.<P>Hotel amenities include indoor pool, complimentary breakfast, business center, high-speed Internet access,

$93Check rates*Min. price over next 30 days

SpringHill Suites by Marriott Florence -  - photo
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SpringHill Suites by Marriott Florence3 																Stars

2670 Hospitality Boulevard - 29501 Florence - See on mapFor GPS & mapping systems use - 2670 Hospitality Blvd, Florence SC 29501. Celebrate life and great travel at SpringHill Suites, Florence SC. Marriott's studio suite hotel is designed with up to 25% more room for

$109Check rates*Min. price over next 30 days

Holiday Inn Express Hotel & Suites FLORENCE I-95 & I-20 CIVIC CTR -  - photo
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Holiday Inn Express Hotel & Suites FLORENCE I-95 & I-20 CIVIC CTR3 																Stars

3440 WEST RADIO DRIVE - 29501 Florence - See on mapCome experience the difference at the Holiday Inn Express Hotel & Suites in Florence, SC! Location! Located in the heart of Florence, we are surrounded by many great restaurants and shopping such as the Magnolia M

$93Check rates*Min. price over next 30 days

Days Inn Florence -  - photo
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Days Inn Florence2 																Stars

3783 West Palmetto Street - 29501 Florence - See on mapDays Inn Florence is located three miles from the Civic Center and approximately ten miles from the airport. For the recreationally inclined, there is an outdoor pool on site with hot tub. The tennis courts across

$47Check rates*Min. price over next 30 days

Microtel Inn and Suites Florence -  - photo
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Microtel Inn and Suites Florence2 																Stars

1912 Enterprise Drive - 29502 Florence - See on mapMicrotel Inn and Suites Florence, SC - Enjoy a Quality Hotel Room at a Discount Hotel Price.Enjoy consistency, quality, reasonable prices and great service each time you stay with Microtel Inns and Suites. Microt

$37Check rates*Min. price over next 30 days

Comfort Inn Florence -  - photo
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Comfort Inn Florence2 																Stars

1920 West Lucas Street - 29501 Florence - See on mapWe are a pet friendly hotel and also offer an increased percentage of 20% off for AAA and AARP. All rooms have irons/ironing boards and hairdryers. In-room safe warranty fee: 1.50 per night. Pet Accommodation: 10.0

$65Check rates*Min. price over next 30 days

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