Florence is a top destination in USA, a great place to spend some time on any visit to USA. Discover our selection of hotels in Florence, sorted below by style and amenities, along with our hotel videos to help you make the right choice.

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Americas Best Value Inn/Florence - - photo
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Americas Best Value Inn/Florence2  Stars

3024 TV Road - 29501 Florence - See on mapFeaturing a superb location and offering convenient accommodation, the Americas Best Value Inn is the perfect place to relax for both corporate and leisure travellers.<p><b>Location</b><br />Americas Best Value Inn

$45Check rates*Min. price over next 30 days

Howard Johnson Express Inn and Suites Florence SC - - photo
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Howard Johnson Express Inn and Suites Florence SC2  Stars

3821 Bancroft Road - 29501 Florence - See on mapFeaturing an elegant decor and a warm hospitality, Howard Johnson welcomes you for an unforgettable vacation.<p><b>Location</b><br />Conveniently located off I-95, just 3 miles south of the 1-20 intersection, Howar

$45Check rates*Min. price over next 30 days

Super 8 Motel Florence (SC) - - photo
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Super 8 Motel Florence (SC)2  Stars

1832 1/2 Lucas Street I-95 Exit 164 Behind CitgoFlorenceSC 29501 -  Florence - See on mapFeaturing beautiful accommodation and pleasant ambience, this property welcomes you for an unforgettable vacation.<p><b>Location</b><br />Located easily accessible from the 1-95, the Super 8 Motel is 16 kilometres

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Ramada Hotel Florence - - photo
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Ramada Hotel Florence2  Stars

3311 Meadors Road I 95 and US 76 Exit 157FlorenceSC 29502 -  Florence - See on mapOffering comfortable accommodation and convenient facilities, the Ramada Hotel Florence is an ideal place to spend your relaxing vacation.<p><b>Location</b><br />The Ramada Hotel Florence is conveniently located at

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Ramada Inn Florence - - photo
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Ramada Inn Florence2  Stars

2038 West Lucas Street I-95 Exit 164 Highway 52FlorenceSC 29501 -  Florence - See on mapAssuring comfortable accommodation with quality service, the Ramada Inn Florence offers an inviting atmosphere and the most gracious hospitality to its guests.<p><b>Location</b><br />Located at I-95 and Exit 164, t

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Days Inn Florence (SC)2  Stars

3783 W Palmetto St, Florence, SC 29501, USA - 29501 Florence - See on mapDays Inn Florence is a modern hotel, well located and within easy reach from the shopping centres like Magnolia Mall and Florence Mall.<p><b>Location</b><br/>Located at half way point between New York and Miami, Da

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Days Inn Florence - - photo
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Days Inn Florence2  Stars

2111 West Lucas Street I-95 I-95 & Highway 52 Exit 164FlorenceSC 29501 -  Florence - See on mapThe Days Inn Florence provides the perfect setting and accommodation for spending a memorable stay with family and friends.<p><b>Location</b><br />The Days Inn Florence is located at North Exit 164 I-95 and is just

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Holiday Inn Express Hotel & Suites Civic Center I-95 & I-20 - - photo
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Holiday Inn Express Hotel & Suites Civic Center I-95 & I-202  Stars

3440 West Radio Drive - 29501 Florence - See on mapOffering a warm and friendly welcome, Holiday Inn Express Hotel and Suites Civic Center is a perfect place for you to reside and explore the surrounding areas.<p><b>Location</b><br />Holiday Inn Express Hotel and S

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Holiday Inn Hotel & Suites FLORENCE SC @ I-95 & US HWY 52 - - photo
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Holiday Inn Hotel & Suites FLORENCE SC @ I-95 & US HWY 524  Stars

1819 Lucas St - 29501 Florence - See on mapHoliday Inn Hotel and Suites Florence, with its charming and exclusive ambience, is a superb setting for business and leisure travellers alike.<p><b>Location</b><br />Conveniently located off I-95, exit 164, in Flo

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Holiday Inn Express Hotel & Suites Florence I-95 @ Highway 327 - - photo
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Holiday Inn Express Hotel & Suites Florence I-95 @ Highway 3272  Stars

2101 Florence Harllee Boulevard I-95Exit 170 Highway 327 Williston RoadFlorence SC 29506 -  Florence - See on mapHoliday Inn Express Hotel and Suites Florence offers all those amenities and services needed to make your stay a productive and enjoyable one.<p><b>Location</b><br />This premiere hotel is superbly located in the s

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Econo Lodge Timmonsville - - photo
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Econo Lodge Timmonsville4  Stars

2200 Cale Yarborough Hwy, Timmonsville, SC 29161, USA - 29161 Florence - See on mapWith a unique atmosphere, special hospitality and convenient facilities, the hotel offers excellent accommodation that makes you to feel at home.<p><b>Location</b><br />Conveniently located off Interstate 95, the E

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Econo Lodge North Florence - - photo
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Econo Lodge North Florence4  Stars

1811 W Lucas St, Florence, SC 29501, USA - 29501 Florence - See on mapBoasting exceptional accommodation and cordial hospitality, the Econo Lodge North Florence is an excellent venue for leisure travellers.<p><b>Location</b><br />Conveniently located off Interstate 95, this property

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Travelodge Florence (SC) - - photo
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Travelodge Florence (SC)2  Stars

3783A West Palmetto Street Exit 157 off I-95FlorenceSC 29502 -  Florence - See on mapProviding all the modern facilities and conveniences, this property is an ideal place for a wonderful and enjoyable vacation.<p><b>Location</b><br />Conveniently located on I-95 at Exit 157, the Travelodge Florence

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Americas Best Value Inn Darlington - - photo
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Americas Best Value Inn Darlington2  Stars

705 Washington St, Darlington, SC 29532, USA - 29532 Florence - See on mapOffering comfortable accommodation, the Americas Best Value Inn in Darlington is an ideal choice for an unforgettable experience.<p><b>Location</b><br />Placed in beautiful South Carolina, the Americas Best Value I

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Wingate by Wyndham Florence - - photo
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Wingate by Wyndham Florence3  Stars

2123 West Lucas Street I-95 exit 164 Highway 52 NorthFlorenceSC 29501 -  Florence - See on mapOffering expected facilities and comforts, Wingate by Wyndham Florence is an ideal place for a pleasant as well as a relaxing stay.<p><b>Location</b><br />Conveniently located close to the areas main businesses and

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